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Differential effects of the cell cycle inhibitor, olomoucine, on functional recovery and on responses of peri-infarct microglia and astrocytes following photothrombotic stroke in rats
BACKGROUND: Following stroke, changes in neuronal connectivity in tissue surrounding the infarct play an important role in both spontaneous recovery of neurological function and in treatment-induced improvements in function. Microglia and astrocytes influence this process through direct interactions...
Autores principales: | Yew, Wai Ping, Djukic, Natalia D., Jayaseelan, Jaya S. P., Woodman, Richard J., Muyderman, Hakan, Sims, Neil R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325288/ https://www.ncbi.nlm.nih.gov/pubmed/34332596 http://dx.doi.org/10.1186/s12974-021-02208-w |
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