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Structural basis for ligand binding modes of CTP synthase

Cytidine triphosphate synthase (CTPS), which comprises an ammonia ligase domain and a glutamine amidotransferase domain, catalyzes the final step of de novo CTP biosynthesis. The activity of CTPS is regulated by the binding of four nucleotides and glutamine. While glutamine serves as an ammonia dono...

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Detalles Bibliográficos
Autores principales:	Zhou, Xian, Guo, Chen-Jun, Chang, Chia-Chun, Zhong, Jiale, Hu, Huan-Huan, Lu, Guang-Ming, Liu, Ji-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325340/ https://www.ncbi.nlm.nih.gov/pubmed/34301892 http://dx.doi.org/10.1073/pnas.2026621118

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