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Identifying compounds that prevent the binding of the SARS-CoV-2 S-protein to ACE2

We investigated compounds selected by molecular docking to identify a specific treatment for COVID-19 that decreases the interaction between angiotensin-converting enzyme 2 (ACE2) and the receptor-binding domain (RBD) of SARS-CoV-2. Five compounds that interact with ACE2 amino acids Gln24, Asp30, Hi...

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Detalles Bibliográficos
Autores principales:	Benítez-Cardoza, Claudia Guadalupe, Vique-Sánchez, José Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325380/ https://www.ncbi.nlm.nih.gov/pubmed/34358993 http://dx.doi.org/10.1016/j.compbiomed.2021.104719

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