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Large chromosomal deletions and impaired homologous recombination repairing in HEK293T cells exposed to polychlorinated biphenyl 153

BACKGROUND: Polychlorinated biphenyls (PCBs) are persistent pollutants with carcinogenesis and mutagenesis effects which have been closely associated with PCBs-induced DNA damage. However, the detailed DNA damage events and corresponding pathway alterations under PCBs poisoning is still not well und...

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Detalles Bibliográficos
Autores principales: Li, Jiaci, Jing, Yaqing, Liu, Yi, Ru, Yawei, Ju, Mingyan, Zhao, Yuxia, Li, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325425/
https://www.ncbi.nlm.nih.gov/pubmed/34395077
http://dx.doi.org/10.7717/peerj.11816