New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles

The phthalocyanine (Pc) and naphthalocyanine (Nc) nanoagents have drawn much attention as contrast agents for photoacoustic (PA) imaging due to their large extinction coefficients and long absorption wavelengths in the near-infrared region. Many investigations have been conducted to enhance Pc/Ncs&#...

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Detalles Bibliográficos
Autores principales: Park, Eun-Yeong, Oh, Donghyeon, Park, Sinyoung, Kim, Wangyu, Kim, Chulhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325568/
https://www.ncbi.nlm.nih.gov/pubmed/34368604
http://dx.doi.org/10.1063/5.0047660
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author Park, Eun-Yeong
Oh, Donghyeon
Park, Sinyoung
Kim, Wangyu
Kim, Chulhong
author_facet Park, Eun-Yeong
Oh, Donghyeon
Park, Sinyoung
Kim, Wangyu
Kim, Chulhong
author_sort Park, Eun-Yeong
collection PubMed
description The phthalocyanine (Pc) and naphthalocyanine (Nc) nanoagents have drawn much attention as contrast agents for photoacoustic (PA) imaging due to their large extinction coefficients and long absorption wavelengths in the near-infrared region. Many investigations have been conducted to enhance Pc/Ncs' photophysical properties and address their poor solubility in an aqueous solution. Many diverse strategies have been adopted, including centric metal chelation, structure modification, and peripheral substitution. This review highlights recent advances on Pc/Nc-based PA agents and their extended use for multiplexed biomedical imaging, multimodal diagnostic imaging, and image-guided phototherapy.
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spelling pubmed-83255682021-08-05 New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles Park, Eun-Yeong Oh, Donghyeon Park, Sinyoung Kim, Wangyu Kim, Chulhong APL Bioeng Reviews The phthalocyanine (Pc) and naphthalocyanine (Nc) nanoagents have drawn much attention as contrast agents for photoacoustic (PA) imaging due to their large extinction coefficients and long absorption wavelengths in the near-infrared region. Many investigations have been conducted to enhance Pc/Ncs' photophysical properties and address their poor solubility in an aqueous solution. Many diverse strategies have been adopted, including centric metal chelation, structure modification, and peripheral substitution. This review highlights recent advances on Pc/Nc-based PA agents and their extended use for multiplexed biomedical imaging, multimodal diagnostic imaging, and image-guided phototherapy. AIP Publishing LLC 2021-07-30 /pmc/articles/PMC8325568/ /pubmed/34368604 http://dx.doi.org/10.1063/5.0047660 Text en © 2021 Author(s). https://creativecommons.org/licenses/by/4.0/© 2021 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Reviews
Park, Eun-Yeong
Oh, Donghyeon
Park, Sinyoung
Kim, Wangyu
Kim, Chulhong
New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles
title New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles
title_full New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles
title_fullStr New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles
title_full_unstemmed New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles
title_short New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles
title_sort new contrast agents for photoacoustic imaging and theranostics: recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325568/
https://www.ncbi.nlm.nih.gov/pubmed/34368604
http://dx.doi.org/10.1063/5.0047660
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