Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the death of midbrain dopamine neurons. The pathogenesis of PD is poorly understood, though misfolded and/or aggregated forms of the protein α-synuclein have been implicated in several neurodegenerative disease processes, incl...

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Detalles Bibliográficos
Autores principales: Chou, Tsui-Wen, Chang, Nydia P., Krishnagiri, Medha, Patel, Aisha P., Lindman, Marissa, Angel, Juan P., Kung, Po-Lun, Atkins, Colm, Daniels, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325686/
https://www.ncbi.nlm.nih.gov/pubmed/34333522
http://dx.doi.org/10.1038/s41419-021-04049-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325686/
https://www.ncbi.nlm.nih.gov/pubmed/34333522
http://dx.doi.org/10.1038/s41419-021-04049-0

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