TRAIL-receptor 2—a novel negative regulator of p53

TNF-related apoptosis-inducing ligand (TRAIL) receptor 2 (TRAIL-R2) can induce apoptosis in cancer cells upon crosslinking by TRAIL. However, TRAIL-R2 is highly expressed by many cancers suggesting pro-tumor functions. Indeed, TRAIL/TRAIL-R2 also activate pro-inflammatory pathways enhancing tumor ce...

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Detalles Bibliográficos
Autores principales: Willms, Anna, Schupp, Hella, Poelker, Michelle, Adawy, Alshaimaa, Debus, Jan Frederik, Hartwig, Torsten, Krichel, Tim, Fritsch, Jürgen, Singh, Steven, Walczak, Henning, von Karstedt, Silvia, Schäfer, Heiner, Trauzold, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325694/
https://www.ncbi.nlm.nih.gov/pubmed/34333527
http://dx.doi.org/10.1038/s41419-021-04048-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325694/
https://www.ncbi.nlm.nih.gov/pubmed/34333527
http://dx.doi.org/10.1038/s41419-021-04048-1

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