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Retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda

BACKGROUND: Retention in HIV care contributes to antiretroviral therapy adherence, which is a key factor for improved treatment outcomes and prevention of drug resistance. However, HIV treatment among the youths is characterized by loss to follow up, poor adherence to ART, risk of treatment failure...

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Autores principales: Muwanguzi, Moses, Lugobe, Henry Mark, Ssemwanga, Elastus, Lule, Allan Phillip, Atwiine, Elizabeth, Kirabira, Vincent, Stella, Ann K., Ashaba, Scholastic, Rukundo, Godfrey Zari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325848/
https://www.ncbi.nlm.nih.gov/pubmed/34332556
http://dx.doi.org/10.1186/s12889-021-11547-5
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author Muwanguzi, Moses
Lugobe, Henry Mark
Ssemwanga, Elastus
Lule, Allan Phillip
Atwiine, Elizabeth
Kirabira, Vincent
Stella, Ann K.
Ashaba, Scholastic
Rukundo, Godfrey Zari
author_facet Muwanguzi, Moses
Lugobe, Henry Mark
Ssemwanga, Elastus
Lule, Allan Phillip
Atwiine, Elizabeth
Kirabira, Vincent
Stella, Ann K.
Ashaba, Scholastic
Rukundo, Godfrey Zari
author_sort Muwanguzi, Moses
collection PubMed
description BACKGROUND: Retention in HIV care contributes to antiretroviral therapy adherence, which is a key factor for improved treatment outcomes and prevention of drug resistance. However, HIV treatment among the youths is characterized by loss to follow up, poor adherence to ART, risk of treatment failure and high mortality rates compared to young children and adults. There is limited information about factors associated with retention of youths in HIV care in rural settings in Uganda. We aimed to determine retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda. METHODS: A cross-sectional study was conducted among youths aged 15–24 years who were receiving care at the HIV clinic at Kabuyanda HC IV who had been in care for at least 1 year before the study. We used an interviewer-administered questionnaire to collect socio-demographic information. Participant chart abstraction was used to collect information on HIV clinic attendance. We collected information on HIV related stigma using the 40-item Berger Stigma Scale. Chi-square test and multivariable logistic regression analysis were used to determine the factors associated with retention in HIV care with a significance level of < 0.05. Retention in HIV care was, defined as having sought care at least once per quarter in the 12 months prior to the study. RESULTS: We enrolled 102 participants with a mean age of 20.95 (SD ± 3.07) years. Two thirds (65.7%) of the youths had been retained in HIV care in the previous 12 months. In adjusted analyses, being male, married and had perinatally acquired HIV were independently associated with retention in HIV care. The association between HIV related stigma and retention in HIV care was not statistically significant. CONCLUSION: Retaining adolescents and young adults in HIV care in rural southwestern Uganda is still much lower than the WHO target of 90%. Being male, having perinatally acquired HIV and married or in a relationship are associated with retention in HIV care. Interventions targeting adolescents and young adults living with HIV are necessary to improve retention in HIV care to the WHO target of 90%. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-11547-5.
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spelling pubmed-83258482021-08-02 Retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda Muwanguzi, Moses Lugobe, Henry Mark Ssemwanga, Elastus Lule, Allan Phillip Atwiine, Elizabeth Kirabira, Vincent Stella, Ann K. Ashaba, Scholastic Rukundo, Godfrey Zari BMC Public Health Research Article BACKGROUND: Retention in HIV care contributes to antiretroviral therapy adherence, which is a key factor for improved treatment outcomes and prevention of drug resistance. However, HIV treatment among the youths is characterized by loss to follow up, poor adherence to ART, risk of treatment failure and high mortality rates compared to young children and adults. There is limited information about factors associated with retention of youths in HIV care in rural settings in Uganda. We aimed to determine retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda. METHODS: A cross-sectional study was conducted among youths aged 15–24 years who were receiving care at the HIV clinic at Kabuyanda HC IV who had been in care for at least 1 year before the study. We used an interviewer-administered questionnaire to collect socio-demographic information. Participant chart abstraction was used to collect information on HIV clinic attendance. We collected information on HIV related stigma using the 40-item Berger Stigma Scale. Chi-square test and multivariable logistic regression analysis were used to determine the factors associated with retention in HIV care with a significance level of < 0.05. Retention in HIV care was, defined as having sought care at least once per quarter in the 12 months prior to the study. RESULTS: We enrolled 102 participants with a mean age of 20.95 (SD ± 3.07) years. Two thirds (65.7%) of the youths had been retained in HIV care in the previous 12 months. In adjusted analyses, being male, married and had perinatally acquired HIV were independently associated with retention in HIV care. The association between HIV related stigma and retention in HIV care was not statistically significant. CONCLUSION: Retaining adolescents and young adults in HIV care in rural southwestern Uganda is still much lower than the WHO target of 90%. Being male, having perinatally acquired HIV and married or in a relationship are associated with retention in HIV care. Interventions targeting adolescents and young adults living with HIV are necessary to improve retention in HIV care to the WHO target of 90%. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-11547-5. BioMed Central 2021-07-31 /pmc/articles/PMC8325848/ /pubmed/34332556 http://dx.doi.org/10.1186/s12889-021-11547-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Muwanguzi, Moses
Lugobe, Henry Mark
Ssemwanga, Elastus
Lule, Allan Phillip
Atwiine, Elizabeth
Kirabira, Vincent
Stella, Ann K.
Ashaba, Scholastic
Rukundo, Godfrey Zari
Retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda
title Retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda
title_full Retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda
title_fullStr Retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda
title_full_unstemmed Retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda
title_short Retention in HIV care and associated factors among youths aged 15–24 years in rural southwestern Uganda
title_sort retention in hiv care and associated factors among youths aged 15–24 years in rural southwestern uganda
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325848/
https://www.ncbi.nlm.nih.gov/pubmed/34332556
http://dx.doi.org/10.1186/s12889-021-11547-5
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