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Aurora kinase A (AURKA) promotes the progression and imatinib resistance of advanced gastrointestinal stromal tumors

BACKGROUND: Gastrointestinal stromal tumor (GIST) is a common tumor that originates from the alimentary system mesenchyme. Compared to typical gastrointestinal carcinomas, GISTs exhibit unique malignant behaviors. Bioinformatic tools and subsequent experiments were applied to investigate novel targe...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaobin, Wang, Jinhai, Lu, Sen, Fan, Weina, Wang, Weilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325869/
https://www.ncbi.nlm.nih.gov/pubmed/34332577
http://dx.doi.org/10.1186/s12935-021-02111-7