Cargando…

SUMOylated non-canonical polycomb PRC1.6 complex as a prerequisite for recruitment of transcription factor RBPJ

BACKGROUND: Notch signaling controls cell fate decisions in many contexts during development and adult stem cell homeostasis and, when dysregulated, leads to carcinogenesis. The central transcription factor RBPJ assembles the Notch coactivator complex in the presence of Notch signaling, and represse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sotomska, Małgorzata, Liefke, Robert, Ferrante, Francesca, Schwederski, Heiko, Oswald, Franz, Borggrefe, Tilman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325870/ https://www.ncbi.nlm.nih.gov/pubmed/34332624 http://dx.doi.org/10.1186/s13072-021-00412-9

Ejemplares similares

Interdependence of PRC1 and PRC2 for recruitment to Polycomb Response Elements
por: Kahn, Tatyana G., et al.
Publicado: (2016)

Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1
por: de Potter, Bastiaan, et al.
Publicado: (2023)

Notch-dependent and -independent functions of transcription factor RBPJ
por: Friedrich, Tobias, et al.
Publicado: (2022)

Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing
por: Moussa, Hagar F., et al.
Publicado: (2019)

Polycomb-like proteins link the PRC2 complex to CpG islands
por: Li, Haojie, et al.
Publicado: (2017)

The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3
por: Hall, Daniel, et al.
Publicado: (2022)

Structure and Function of the Polycomb Repressive Complexes PRC1 and PRC2
por: Angrand, Pierre-Olivier
Publicado: (2022)

Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site
por: Yuan, Zhenyu, et al.
Publicado: (2019)

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1
por: Glancy, Eleanor, et al.
Publicado: (2023)

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
por: Blackledge, Neil P., et al.
Publicado: (2014)

CBF-1 Promotes the Establishment and Maintenance of HIV Latency by Recruiting Polycomb Repressive Complexes, PRC1 and PRC2, at HIV LTR
por: Sharma, Adhikarimayum Lakhikumar, et al.
Publicado: (2020)

Rif1 interacts with non-canonical polycomb repressive complex PRC1.6 to regulate mouse embryonic stem cells fate potential
por: Li, Lu, et al.
Publicado: (2022)

Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes
por: Diéguez-Hurtado, Rodrigo, et al.
Publicado: (2019)

The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis
por: Yuan, Liangbing, et al.
Publicado: (2020)

PRC1 Catalytic Activity Is Central to Polycomb System Function
por: Blackledge, Neil P., et al.
Publicado: (2020)

MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6
por: Stielow, Bastian, et al.
Publicado: (2018)

Polycomb-like Proteins in Gene Regulation and Cancer
por: Fischer, Sabrina, et al.
Publicado: (2023)

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2
por: Alecki, Célia, et al.
Publicado: (2020)

Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops
por: Williamson, Iain, et al.
Publicado: (2023)

Independent domains for recruitment of PRC1 and PRC2 by human XIST
por: Dixon-McDougall, Thomas, et al.
Publicado: (2021)

Evolutionary adaptation of the Polycomb repressive complex 2
por: Fischer, Sabrina, et al.
Publicado: (2022)

Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC
por: Frey, Felice, et al.
Publicado: (2016)

Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice
por: Rossi, Alessandra, et al.
Publicado: (2016)

Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration
por: von Schimmelmann, Melanie, et al.
Publicado: (2016)

Correction: Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops
por: Williamson, Iain, et al.
Publicado: (2023)

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing
por: Pintacuda, Greta, et al.
Publicado: (2017)

Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation
por: Zhang, Jing, et al.
Publicado: (2023)

Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity
por: Majewski, Ian J, et al.
Publicado: (2008)

AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2
por: Kim, Hana, et al.
Publicado: (2009)

Polycomb-like 2 regulates PRC2 components to affect proliferation in glioma cells
por: Wang, Fei, et al.
Publicado: (2020)

Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression
por: Fursova, Nadezda A., et al.
Publicado: (2019)

Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment
por: Cooper, Sarah, et al.
Publicado: (2014)

An RBPJ-Drosophila Model Reveals Dependence of RBPJ Protein Stability on the Formation of Transcription–Regulator Complexes
por: Gahr, Bernd M., et al.
Publicado: (2019)

Setting the Stage for Notch: The Drosophila Su(H)-Hairless Repressor Complex
por: Borggrefe, Tilman, et al.
Publicado: (2016)

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2
por: Cooper, Sarah, et al.
Publicado: (2016)

RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes
por: Rose, Nathan R, et al.
Publicado: (2016)

Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB cooperate for developmental stability
por: Dardalhon-Cuménal, Delphine, et al.
Publicado: (2018)

Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ
por: Hurtado, Cecilia, et al.
Publicado: (2019)

RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation
por: Pan, Leiling, et al.
Publicado: (2023)

Hierarchical recruitment of Polycomb complexes revisited
por: Dorafshan, Eshagh, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_d39m1lcjn4kvqe9gaj7b72u2tl