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JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes

Macropinocytosis allows cells to take up extracellular material in a non-selective manner into large vesicles called macropinosomes. After internalization, macropinosomes acquire phosphatidylinositol 3-phosphate (PtdIns3P) on their limiting membrane as they mature into endosomal-like vesicles. The m...

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Detalles Bibliográficos
Autores principales: Tan, Kia Wee, Nähse, Viola, Campsteijn, Coen, Brech, Andreas, Schink, Kay Oliver, Stenmark, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325962/
https://www.ncbi.nlm.nih.gov/pubmed/34109410
http://dx.doi.org/10.1242/jcs.258495