Efficacy of Gamma Knife radiosurgery in the management of pituitary prolactinoma

BACKGROUND: Gamma Knife radiosurgery (GKR) has been widely used in the management of a variety of intracranial tumors, including pituitary adenomas. Pituitary prolactinoma (Prs) is one of the most common types of these adenomas. METHODS: This prospective study included 50 patients with pituitary Prs...

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Detalles Bibliográficos
Autores principales: Arkawazi, Bassam Mahmood Flamerz, Al Atraqchi, Ahmed, Adnan, Arjan, Dheyab, Shaymaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326074/
https://www.ncbi.nlm.nih.gov/pubmed/34345497
http://dx.doi.org/10.25259/SNI_230_2021
Descripción
Sumario:BACKGROUND: Gamma Knife radiosurgery (GKR) has been widely used in the management of a variety of intracranial tumors, including pituitary adenomas. Pituitary prolactinoma (Prs) is one of the most common types of these adenomas. METHODS: This prospective study included 50 patients with pituitary Prs over a period from June 2017 to June 2018 at the Neurosciences Hospital, Baghdad/Iraq. The GKR procedure was performed using the Leksell Gamma Knife(®) Perfexion™, 192 beams of Cobalt 60 radiation were delivered through the intact skull to the pituitary Prs. RESULTS: There is a significant female predominance 32 (72%). The results after 6 months of GKR showed significant improvement regarding the size of adenoma, prolactin hormone level, contrast enhancement on MRI, and medical treatment. CONCLUSION: The study showed that the GKR is a safe and effective modality of treatment in the management of pituitary Prs.

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