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Crosstalk between hypoxia-sensing ULK1/2 and YAP-driven glycolysis fuels pancreatic ductal adenocarcinoma development

Autophagy and glycolysis are two catabolic processes that manipulate pancreatic ductal adenocarcinoma (PDAC) development in response to hypoxia sensing, yet the underlying mechanism of how they are interlinked remain elusive. Methods: The functional roles of Unc-51 like kinase 1 and 2 (ULK1/2) in py...

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Detalles Bibliográficos
Autores principales:	Jia, Yu, Li, Hui-Yan, Wang, Ying, Wang, Jue, Zhu, Jing-Wen, Wei, Yan-Yan, Lou, Lu, Chen, Xing, Mo, Shi-Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326115/ https://www.ncbi.nlm.nih.gov/pubmed/34345207 http://dx.doi.org/10.7150/ijbs.60018

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