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Myonuclear transcriptional dynamics in response to exercise following satellite cell depletion
Skeletal muscle is composed of post-mitotic myofibers that form a syncytium containing hundreds of myonuclei. Using a progressive exercise training model in the mouse and single nucleus RNA-sequencing (snRNA-seq) for high-resolution characterization of myonuclear transcription, we show myonuclear fu...
Autores principales: | Wen, Yuan, Englund, Davis A., Peck, Bailey D., Murach, Kevin A., McCarthy, John J., Peterson, Charlotte A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326190/ https://www.ncbi.nlm.nih.gov/pubmed/34368654 http://dx.doi.org/10.1016/j.isci.2021.102838 |
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