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Combinatorial actions of glucocorticoid and mineralocorticoid stress hormone receptors are required for preventing neurodegeneration of the mouse hippocampus
Chronic stress contributes to numerous human pathologies including cognition impairments and psychiatric disorders. Glucocorticoids are primary stress hormones that activate two closely related nuclear receptors, the glucocorticoid (GR) and mineralocorticoid receptor (MR), that are both highly expre...
Autores principales: | Oakley, Robert H., Whirledge, Shannon D., Petrillo, Maria G., Riddick, Natallia V., Xu, Xiaojiang, Moy, Sheryl S., Cidlowski, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326231/ https://www.ncbi.nlm.nih.gov/pubmed/34368410 http://dx.doi.org/10.1016/j.ynstr.2021.100369 |
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