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New anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures
BACKGROUND: There is little data available on the role of new anti-reflux plastic stents (ARPSs). AIM: To compare the use of ARPSs with that of traditional plastic stents (TPSs) for patients with biliary strictures. METHODS: Consecutive patients with biliary strictures who underwent first endoscopic...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326253/ https://www.ncbi.nlm.nih.gov/pubmed/34366630 http://dx.doi.org/10.3748/wjg.v27.i28.4697 |
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author | Yuan, Xiang-Lei Ye, Lian-Song Zeng, Xian-Hui Tan, Qing-Hua Mou, Yi Liu, Wei Wu, Chun-Cheng Yang, Hang Hu, Bing |
author_facet | Yuan, Xiang-Lei Ye, Lian-Song Zeng, Xian-Hui Tan, Qing-Hua Mou, Yi Liu, Wei Wu, Chun-Cheng Yang, Hang Hu, Bing |
author_sort | Yuan, Xiang-Lei |
collection | PubMed |
description | BACKGROUND: There is little data available on the role of new anti-reflux plastic stents (ARPSs). AIM: To compare the use of ARPSs with that of traditional plastic stents (TPSs) for patients with biliary strictures. METHODS: Consecutive patients with biliary strictures who underwent first endoscopic biliary stenting between February 2016 and May 2019 were included. The onset of stent-related cholangitis, stent patency, clinical success, and other adverse events were evaluated. RESULTS: Sixty-seven patients in the ARPS group and 66 patients in the TPS group were included in the final analyses. Fewer patients experienced stent-related cholangitis in the ARPS group than that in the TPS group (8 patients vs 18 patients; P = 0.030). The median time till the onset of first stent-related cholangitis was later in the ARPS group than that in the TPS group (128.5 d vs 76 d; P = 0.039). The cumulative median stent patency in the ARPS group was 185 d, which was significantly longer than that in the TPS group (133 d; P = 0.001). The clinical success rates and other adverse events did not significantly differ between both groups. CONCLUSION: Placement of new ARPS might be a safe and effective optional therapeutic strategy to reduce the risk of stent-related cholangitis and prolong stent patency. |
format | Online Article Text |
id | pubmed-8326253 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-83262532021-08-06 New anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures Yuan, Xiang-Lei Ye, Lian-Song Zeng, Xian-Hui Tan, Qing-Hua Mou, Yi Liu, Wei Wu, Chun-Cheng Yang, Hang Hu, Bing World J Gastroenterol Retrospective Study BACKGROUND: There is little data available on the role of new anti-reflux plastic stents (ARPSs). AIM: To compare the use of ARPSs with that of traditional plastic stents (TPSs) for patients with biliary strictures. METHODS: Consecutive patients with biliary strictures who underwent first endoscopic biliary stenting between February 2016 and May 2019 were included. The onset of stent-related cholangitis, stent patency, clinical success, and other adverse events were evaluated. RESULTS: Sixty-seven patients in the ARPS group and 66 patients in the TPS group were included in the final analyses. Fewer patients experienced stent-related cholangitis in the ARPS group than that in the TPS group (8 patients vs 18 patients; P = 0.030). The median time till the onset of first stent-related cholangitis was later in the ARPS group than that in the TPS group (128.5 d vs 76 d; P = 0.039). The cumulative median stent patency in the ARPS group was 185 d, which was significantly longer than that in the TPS group (133 d; P = 0.001). The clinical success rates and other adverse events did not significantly differ between both groups. CONCLUSION: Placement of new ARPS might be a safe and effective optional therapeutic strategy to reduce the risk of stent-related cholangitis and prolong stent patency. Baishideng Publishing Group Inc 2021-07-28 2021-07-28 /pmc/articles/PMC8326253/ /pubmed/34366630 http://dx.doi.org/10.3748/wjg.v27.i28.4697 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Retrospective Study Yuan, Xiang-Lei Ye, Lian-Song Zeng, Xian-Hui Tan, Qing-Hua Mou, Yi Liu, Wei Wu, Chun-Cheng Yang, Hang Hu, Bing New anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures |
title | New anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures |
title_full | New anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures |
title_fullStr | New anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures |
title_full_unstemmed | New anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures |
title_short | New anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures |
title_sort | new anti-reflux plastic stent to reduce the risk of stent-related cholangitis in the treatment of biliary strictures |
topic | Retrospective Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326253/ https://www.ncbi.nlm.nih.gov/pubmed/34366630 http://dx.doi.org/10.3748/wjg.v27.i28.4697 |
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