SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells

OBJECTIVE: Members of the adhesion G protein-coupled receptor (aGPCR) subfamily are important actors in metabolic processes, with GPR56 (ADGRG1) emerging as a possible target for type 2 diabetes therapy. GPR56 can be activated by collagen III, its endogenous ligand, and by a synthetic seven amino-ac...

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Detalles Bibliográficos
Autores principales: Olaniru, Oladapo E., Cheng, Jordan, Ast, Julia, Arvaniti, Anastasia, Atanes, Patricio, Huang, Guo C., King, Aileen J.F., Jones, Peter M., Broichhagen, Johannes, Hodson, David J., Persaud, Shanta J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326393/
https://www.ncbi.nlm.nih.gov/pubmed/34224919
http://dx.doi.org/10.1016/j.molmet.2021.101285

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