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Tirbanibulin Attenuates Pulmonary Fibrosis by Modulating Src/STAT3 Signaling

Tirbanibulin (KX-01) is the first clinical Src inhibitor of the novel peptidomimetic class that targets the peptide substrate site of Src providing more specificity toward the Src kinase. This study assessed the impact of KX-01 on cobalt chloride (CoCl(2))-treated L929 cells and bleomycin (BLM)-indu...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Ren, Rui, Xu, Zehui, Huang, Haidi, Jiang, Wanglin, Ma, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326405/
https://www.ncbi.nlm.nih.gov/pubmed/34349652
http://dx.doi.org/10.3389/fphar.2021.693906