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RNA Is a Double-Edged Sword in ALS Pathogenesis
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease that affects upper and lower motor neurons. Familial ALS accounts for a small subset of cases (<10–15%) and is caused by dominant mutations in one of more than 10 known genes. Multiple genes have been causall...
Autores principales: | Zaepfel, Benjamin L., Rothstein, Jeffrey D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326408/ https://www.ncbi.nlm.nih.gov/pubmed/34349625 http://dx.doi.org/10.3389/fncel.2021.708181 |
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