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The cross-talk between tumor cells and activated fibroblasts mediated by lactate/BDNF/TrkB signaling promotes acquired resistance to anlotinib in human gastric cancer

Acquired resistance to tyrosine kinase inhibitors (TKIs) is the major obstacle to improve clinical efficacy in cancer patients. The epithelial-stromal interaction in tumor microenvironment influences cancer drug response to TKIs. Anlotinib is a novel oral multi-targeted TKI, and has recently been pr...

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Detalles Bibliográficos
Autores principales:	Jin, Zhijian, Lu, Yifan, Wu, Xiongyan, Pan, Tao, Yu, Zhenjia, Hou, Junyi, Wu, Airong, Li, Jianfang, Yang, Zhongyin, Li, Chen, Yan, Min, Yan, Chao, Zhu, Zhenggang, Liu, Bingya, Qiu, Weihua, Su, Liping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326414/ https://www.ncbi.nlm.nih.gov/pubmed/34315112 http://dx.doi.org/10.1016/j.redox.2021.102076

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