Novel Mannich bases with strong carbonic anhydrases and acetylcholinesterase inhibition effects: 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2(3H)-benzoxazolones

In this study, a new series of Mannich bases, 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2( 3H )-benzoxazolones ( 1a–g ), were synthesized by the Mannich reaction. Inhibitory effects of the newly synthesized compounds towards carbonic anhydrases (CAs) and acetylcholinesterase (AChE) e...

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Detalles Bibliográficos
Autores principales: BiLGiNER, Sinan, ANIL, Barış, KOCA, Mehmet, DEMİR, Yeliz, GÜLÇİN, İlhami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326492/
https://www.ncbi.nlm.nih.gov/pubmed/34385868
http://dx.doi.org/10.3906/kim-2101-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326492/
https://www.ncbi.nlm.nih.gov/pubmed/34385868
http://dx.doi.org/10.3906/kim-2101-25

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