Cargando…

Privacy considerations for sharing genomics data

An increasing amount of attention has been geared towards understanding the privacy risks that arise from sharing genomic data of human origin. Most of these efforts have focused on issues in the context of genomic sequence data, but the popularity of techniques for collecting other types of genome-...

Descripción completa

Detalles Bibliográficos
Autores principales: Oestreich, Marie, Chen, Dingfan, Schultze, Joachim L., Fritz, Mario, Becker, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326502/
https://www.ncbi.nlm.nih.gov/pubmed/34345236
http://dx.doi.org/10.17179/excli2021-4002
_version_ 1783731839652855808
author Oestreich, Marie
Chen, Dingfan
Schultze, Joachim L.
Fritz, Mario
Becker, Matthias
author_facet Oestreich, Marie
Chen, Dingfan
Schultze, Joachim L.
Fritz, Mario
Becker, Matthias
author_sort Oestreich, Marie
collection PubMed
description An increasing amount of attention has been geared towards understanding the privacy risks that arise from sharing genomic data of human origin. Most of these efforts have focused on issues in the context of genomic sequence data, but the popularity of techniques for collecting other types of genome-related data has prompted researchers to investigate privacy concerns in a broader genomic context. In this review, we give an overview of different types of genome-associated data, their individual ways of revealing sensitive information, the motivation to share them as well as established and upcoming methods to minimize information leakage. We further discuss the concise threats that are being posed, who is at risk, and how the risk level compares to potential benefits, all while addressing the topic in the context of modern technology, methodology, and information sharing culture. Additionally, we will discuss the current legal situation regarding the sharing of genomic data in a selection of countries, evaluating the scope of their applicability as well as their limitations. We will finalize this review by evaluating the development that is required in the scientific field in the near future in order to improve and develop privacy-preserving data sharing techniques for the genomic context.
format Online
Article
Text
id pubmed-8326502
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Leibniz Research Centre for Working Environment and Human Factors
record_format MEDLINE/PubMed
spelling pubmed-83265022021-08-02 Privacy considerations for sharing genomics data Oestreich, Marie Chen, Dingfan Schultze, Joachim L. Fritz, Mario Becker, Matthias EXCLI J Review Article An increasing amount of attention has been geared towards understanding the privacy risks that arise from sharing genomic data of human origin. Most of these efforts have focused on issues in the context of genomic sequence data, but the popularity of techniques for collecting other types of genome-related data has prompted researchers to investigate privacy concerns in a broader genomic context. In this review, we give an overview of different types of genome-associated data, their individual ways of revealing sensitive information, the motivation to share them as well as established and upcoming methods to minimize information leakage. We further discuss the concise threats that are being posed, who is at risk, and how the risk level compares to potential benefits, all while addressing the topic in the context of modern technology, methodology, and information sharing culture. Additionally, we will discuss the current legal situation regarding the sharing of genomic data in a selection of countries, evaluating the scope of their applicability as well as their limitations. We will finalize this review by evaluating the development that is required in the scientific field in the near future in order to improve and develop privacy-preserving data sharing techniques for the genomic context. Leibniz Research Centre for Working Environment and Human Factors 2021-07-16 /pmc/articles/PMC8326502/ /pubmed/34345236 http://dx.doi.org/10.17179/excli2021-4002 Text en Copyright © 2021 Oestreich et al. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ) You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Review Article
Oestreich, Marie
Chen, Dingfan
Schultze, Joachim L.
Fritz, Mario
Becker, Matthias
Privacy considerations for sharing genomics data
title Privacy considerations for sharing genomics data
title_full Privacy considerations for sharing genomics data
title_fullStr Privacy considerations for sharing genomics data
title_full_unstemmed Privacy considerations for sharing genomics data
title_short Privacy considerations for sharing genomics data
title_sort privacy considerations for sharing genomics data
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326502/
https://www.ncbi.nlm.nih.gov/pubmed/34345236
http://dx.doi.org/10.17179/excli2021-4002
work_keys_str_mv AT oestreichmarie privacyconsiderationsforsharinggenomicsdata
AT chendingfan privacyconsiderationsforsharinggenomicsdata
AT schultzejoachiml privacyconsiderationsforsharinggenomicsdata
AT fritzmario privacyconsiderationsforsharinggenomicsdata
AT beckermatthias privacyconsiderationsforsharinggenomicsdata