The Clinical Presentation of Culture-positive and Culture-negative, Quantitative Polymerase Chain Reaction (qPCR)-Attributable Shigellosis in the Global Enteric Multicenter Study and Derivation of a Shigella Severity Score: Implications for Pediatric Shigella Vaccine Trials

BACKGROUND: Shigella is a leading cause of childhood diarrhea and target for vaccine development. Microbiologic and clinical case definitions are needed for pediatric field vaccine efficacy trials. METHODS: We compared characteristics of moderate to severe diarrhea (MSD) cases in the Global Enteric...

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Autores principales: Pavlinac, Patricia B, Platts-Mills, James A, Tickell, Kirkby D, Liu, Jie, Juma, Jane, Kabir, Furqan, Nkeze, Joseph, Okoi, Catherine, Operario, Darwin J, Uddin, Jashim, Ahmed, Shahnawaz, Alonso, Pedro L, Antonio, Martin, Becker, Stephen M, Breiman, Robert F, Faruque, Abu S G, Fields, Barry, Gratz, Jean, Haque, Rashidul, Hossain, Anowar, Hossain, M Jahangir, Jarju, Sheikh, Qamar, Farah, Iqbal, Najeeha Talat, Kwambana, Brenda, Mandomando, Inacio, McMurry, Timothy L, Ochieng, Caroline, Ochieng, John B, Ochieng, Melvin, Onyango, Clayton, Panchalingam, Sandra, Kalam, Adil, Aziz, Fatima, Qureshi, Shahida, Ramamurthy, Thandavarayan, Roberts, James H, Saha, Debasish, Sow, Samba O, Stroup, Suzanne E, Sur, Dipika, Tamboura, Boubou, Taniuchi, Mami, Tennant, Sharon M, Roose, Anna, Toema, Deanna, Wu, Yukun, Zaidi, Anita, Nataro, James P, Levine, Myron M, Houpt, Eric R, Kotloff, Karen L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Online Only Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326551/
https://www.ncbi.nlm.nih.gov/pubmed/33044509
http://dx.doi.org/10.1093/cid/ciaa1545

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