Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada

Combined with epidemiological data, whole-genome sequencing (WGS) can help better resolve individual tuberculosis (TB) transmission events to a degree not possible with traditional genotyping. We combine WGS data with patient-level data to calculate the timing of secondary TB among contacts of peopl...

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Autores principales: Romanowski, Kamila, Sobkowiak, Benjamin, Guthrie, Jennifer L, Cook, Victoria J, Gardy, Jennifer L, Johnston, James C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326569/
https://www.ncbi.nlm.nih.gov/pubmed/32812027
http://dx.doi.org/10.1093/cid/ciaa1224
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author Romanowski, Kamila
Sobkowiak, Benjamin
Guthrie, Jennifer L
Cook, Victoria J
Gardy, Jennifer L
Johnston, James C
author_facet Romanowski, Kamila
Sobkowiak, Benjamin
Guthrie, Jennifer L
Cook, Victoria J
Gardy, Jennifer L
Johnston, James C
author_sort Romanowski, Kamila
collection PubMed
description Combined with epidemiological data, whole-genome sequencing (WGS) can help better resolve individual tuberculosis (TB) transmission events to a degree not possible with traditional genotyping. We combine WGS data with patient-level data to calculate the timing of secondary TB among contacts of people diagnosed with active TB in British Columbia, Canada.
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spelling pubmed-83265692021-08-02 Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada Romanowski, Kamila Sobkowiak, Benjamin Guthrie, Jennifer L Cook, Victoria J Gardy, Jennifer L Johnston, James C Clin Infect Dis Brief Reports Combined with epidemiological data, whole-genome sequencing (WGS) can help better resolve individual tuberculosis (TB) transmission events to a degree not possible with traditional genotyping. We combine WGS data with patient-level data to calculate the timing of secondary TB among contacts of people diagnosed with active TB in British Columbia, Canada. Oxford University Press 2020-08-19 /pmc/articles/PMC8326569/ /pubmed/32812027 http://dx.doi.org/10.1093/cid/ciaa1224 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Romanowski, Kamila
Sobkowiak, Benjamin
Guthrie, Jennifer L
Cook, Victoria J
Gardy, Jennifer L
Johnston, James C
Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada
title Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada
title_full Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada
title_fullStr Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada
title_full_unstemmed Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada
title_short Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada
title_sort using whole-genome sequencing to determine the timing of secondary tuberculosis in british columbia, canada
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326569/
https://www.ncbi.nlm.nih.gov/pubmed/32812027
http://dx.doi.org/10.1093/cid/ciaa1224
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