A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma

Lactic acidosis is an extremely rare paraneoplastic manifestation of hematological malignancies, and often carries an extremely poor prognosis. Mantle cell lymphoma is an aggressive and rare form of non-Hodgkin lymphoma. To the best of our knowledge, it is extremely rare to have severe lactic acidos...

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Autores principales: Chan, Kok Hoe, Prabhakar, Laxminarayan, Al-Radideh, Omar, Okwesili, Byron, Are, Gowthami, Shaaban, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326604/
https://www.ncbi.nlm.nih.gov/pubmed/34330169
http://dx.doi.org/10.1177/23247096211034040
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author Chan, Kok Hoe
Prabhakar, Laxminarayan
Al-Radideh, Omar
Okwesili, Byron
Are, Gowthami
Shaaban, Hamid
author_facet Chan, Kok Hoe
Prabhakar, Laxminarayan
Al-Radideh, Omar
Okwesili, Byron
Are, Gowthami
Shaaban, Hamid
author_sort Chan, Kok Hoe
collection PubMed
description Lactic acidosis is an extremely rare paraneoplastic manifestation of hematological malignancies, and often carries an extremely poor prognosis. Mantle cell lymphoma is an aggressive and rare form of non-Hodgkin lymphoma. To the best of our knowledge, it is extremely rare to have severe lactic acidosis in patients with mantle cell lymphoma. In this article, we are reporting a rare case of mantle cell lymphoma diagnosed with typical cluster differentiation (CD markers) in bone marrow examination with persistent lactic acidosis refractory to intravenous hydration that responded well to chemotherapy. Malignant lactic acidosis is a medical emergency that needs rapid evaluation and identification that shows improved prognosis after the introduction of chemotherapy.
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spelling pubmed-83266042021-08-09 A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma Chan, Kok Hoe Prabhakar, Laxminarayan Al-Radideh, Omar Okwesili, Byron Are, Gowthami Shaaban, Hamid J Investig Med High Impact Case Rep Case Report Lactic acidosis is an extremely rare paraneoplastic manifestation of hematological malignancies, and often carries an extremely poor prognosis. Mantle cell lymphoma is an aggressive and rare form of non-Hodgkin lymphoma. To the best of our knowledge, it is extremely rare to have severe lactic acidosis in patients with mantle cell lymphoma. In this article, we are reporting a rare case of mantle cell lymphoma diagnosed with typical cluster differentiation (CD markers) in bone marrow examination with persistent lactic acidosis refractory to intravenous hydration that responded well to chemotherapy. Malignant lactic acidosis is a medical emergency that needs rapid evaluation and identification that shows improved prognosis after the introduction of chemotherapy. SAGE Publications 2021-07-30 /pmc/articles/PMC8326604/ /pubmed/34330169 http://dx.doi.org/10.1177/23247096211034040 Text en © 2021 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Chan, Kok Hoe
Prabhakar, Laxminarayan
Al-Radideh, Omar
Okwesili, Byron
Are, Gowthami
Shaaban, Hamid
A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_full A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_fullStr A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_full_unstemmed A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_short A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_sort rare case of severe lactic acidosis in a patient with mantle cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326604/
https://www.ncbi.nlm.nih.gov/pubmed/34330169
http://dx.doi.org/10.1177/23247096211034040
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