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A case of blaNDM-1-positive Salmonella Kottbus, Denmark, November 2020

We present a case of carbapenemase-producing blaNDM-1-positive Salmonella Kottbus in an 82-year-old Danish man. The blaNDM-1 was also identified in Escherichia coli and Citrobacter freundii in the same patient on the same 43 kb IncN2 plasmid, suggesting in vivo inter-species plasmid transfer. A NCBI...

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Detalles Bibliográficos
Autores principales: Nielsen, Hans Linde, Thomsen, Philip K., Litrup, Eva, Torpdahl, Mia, Overballe-Petersen, Søren, Hansen, Frank, Christensen, Anne Kathrine Schultz, Hasman, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326659/
https://www.ncbi.nlm.nih.gov/pubmed/34212839
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.26.2100569
Descripción
Sumario:We present a case of carbapenemase-producing blaNDM-1-positive Salmonella Kottbus in an 82-year-old Danish man. The blaNDM-1 was also identified in Escherichia coli and Citrobacter freundii in the same patient on the same 43 kb IncN2 plasmid, suggesting in vivo inter-species plasmid transfer. A NCBI BLAST analysis of the plasmid (pAMA003584_NDM-1) identified 12 highly similar plasmids, all originating from east and south-east Asia. This case could be the first confirmed case of blaNDM-1-positive Salmonella not related to travel outside Europe.