Integrative Analysis of HTNV Glycoprotein Derived MHC II Epitopes by In Silico Prediction and Experimental Validation

Hantaan virus (HTNV), the causative pathogen of hemorrhagic fever with renal syndrome (HFRS), is a negative RNA virus belonging to the Orthohantaviridae family. HTNV envelope glycoprotein (GP), encoded by the genomic medium segment, is immunogenic and is therefore a promising vaccine candidate. Majo...

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Detalles Bibliográficos
Autores principales: Sun, Hao, Lu, Zhenhua, Xuan, Guoyun, Liu, Ning, Wang, Tianhu, Liu, Yang, Lan, Mingfu, Xu, Jiahao, Feng, Yuancai, Xu, Shuang, Lu, Yuchen, Sun, Baozeng, Zhang, Jinpeng, Zhang, Xiyang, Sun, Yuanjie, Yang, Shuya, Zhang, Yun, Zhang, Yusi, Cheng, Linfeng, Jiang, Dongbo, Yang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326763/
https://www.ncbi.nlm.nih.gov/pubmed/34350130
http://dx.doi.org/10.3389/fcimb.2021.671694

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