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Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations

Ligand-gated ion channels are critical mediators of electrochemical signal transduction across evolution. Biophysical and pharmacological characterization of these receptor proteins relies on high-quality structures in multiple, subtly distinct functional states. However, structural data in this fam...

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Detalles Bibliográficos
Autores principales:	Rovšnik, Urška, Zhuang, Yuxuan, Forsberg, Björn O, Carroni, Marta, Yvonnesdotter, Linnea, Howard, Rebecca J, Lindahl, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326787/ https://www.ncbi.nlm.nih.gov/pubmed/34210687 http://dx.doi.org/10.26508/lsa.202101011

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