Cargando…

BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound

Automatic and accurate segmentation of breast lesion regions from ultrasonography is an essential step for ultrasound-guided diagnosis and treatment. However, developing a desirable segmentation method is very difficult due to strong imaging artifacts e.g., speckle noise, low contrast and intensity...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yunzhu, Zhang, Ruoxin, Zhu, Lei, Wang, Weiming, Wang, Shengwen, Xie, Haoran, Cheng, Gary, Wang, Fu Lee, He, Xingxiang, Zhang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326799/
https://www.ncbi.nlm.nih.gov/pubmed/34350211
http://dx.doi.org/10.3389/fmolb.2021.698334
_version_ 1783731922847924224
author Wu, Yunzhu
Zhang, Ruoxin
Zhu, Lei
Wang, Weiming
Wang, Shengwen
Xie, Haoran
Cheng, Gary
Wang, Fu Lee
He, Xingxiang
Zhang, Hai
author_facet Wu, Yunzhu
Zhang, Ruoxin
Zhu, Lei
Wang, Weiming
Wang, Shengwen
Xie, Haoran
Cheng, Gary
Wang, Fu Lee
He, Xingxiang
Zhang, Hai
author_sort Wu, Yunzhu
collection PubMed
description Automatic and accurate segmentation of breast lesion regions from ultrasonography is an essential step for ultrasound-guided diagnosis and treatment. However, developing a desirable segmentation method is very difficult due to strong imaging artifacts e.g., speckle noise, low contrast and intensity inhomogeneity, in breast ultrasound images. To solve this problem, this paper proposes a novel boundary-guided multiscale network (BGM-Net) to boost the performance of breast lesion segmentation from ultrasound images based on the feature pyramid network (FPN). First, we develop a boundary-guided feature enhancement (BGFE) module to enhance the feature map for each FPN layer by learning a boundary map of breast lesion regions. The BGFE module improves the boundary detection capability of the FPN framework so that weak boundaries in ambiguous regions can be correctly identified. Second, we design a multiscale scheme to leverage the information from different image scales in order to tackle ultrasound artifacts. Specifically, we downsample each testing image into a coarse counterpart, and both the testing image and its coarse counterpart are input into BGM-Net to predict a fine and a coarse segmentation maps, respectively. The segmentation result is then produced by fusing the fine and the coarse segmentation maps so that breast lesion regions are accurately segmented from ultrasound images and false detections are effectively removed attributing to boundary feature enhancement and multiscale image information. We validate the performance of the proposed approach on two challenging breast ultrasound datasets, and experimental results demonstrate that our approach outperforms state-of-the-art methods.
format Online
Article
Text
id pubmed-8326799
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-83267992021-08-03 BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound Wu, Yunzhu Zhang, Ruoxin Zhu, Lei Wang, Weiming Wang, Shengwen Xie, Haoran Cheng, Gary Wang, Fu Lee He, Xingxiang Zhang, Hai Front Mol Biosci Molecular Biosciences Automatic and accurate segmentation of breast lesion regions from ultrasonography is an essential step for ultrasound-guided diagnosis and treatment. However, developing a desirable segmentation method is very difficult due to strong imaging artifacts e.g., speckle noise, low contrast and intensity inhomogeneity, in breast ultrasound images. To solve this problem, this paper proposes a novel boundary-guided multiscale network (BGM-Net) to boost the performance of breast lesion segmentation from ultrasound images based on the feature pyramid network (FPN). First, we develop a boundary-guided feature enhancement (BGFE) module to enhance the feature map for each FPN layer by learning a boundary map of breast lesion regions. The BGFE module improves the boundary detection capability of the FPN framework so that weak boundaries in ambiguous regions can be correctly identified. Second, we design a multiscale scheme to leverage the information from different image scales in order to tackle ultrasound artifacts. Specifically, we downsample each testing image into a coarse counterpart, and both the testing image and its coarse counterpart are input into BGM-Net to predict a fine and a coarse segmentation maps, respectively. The segmentation result is then produced by fusing the fine and the coarse segmentation maps so that breast lesion regions are accurately segmented from ultrasound images and false detections are effectively removed attributing to boundary feature enhancement and multiscale image information. We validate the performance of the proposed approach on two challenging breast ultrasound datasets, and experimental results demonstrate that our approach outperforms state-of-the-art methods. Frontiers Media S.A. 2021-07-19 /pmc/articles/PMC8326799/ /pubmed/34350211 http://dx.doi.org/10.3389/fmolb.2021.698334 Text en Copyright © 2021 Wu, Zhang, Zhu, Wang, Wang, Xie, Cheng, Wang, He and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Molecular Biosciences
Wu, Yunzhu
Zhang, Ruoxin
Zhu, Lei
Wang, Weiming
Wang, Shengwen
Xie, Haoran
Cheng, Gary
Wang, Fu Lee
He, Xingxiang
Zhang, Hai
BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound
title BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound
title_full BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound
title_fullStr BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound
title_full_unstemmed BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound
title_short BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound
title_sort bgm-net: boundary-guided multiscale network for breast lesion segmentation in ultrasound
topic Molecular Biosciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326799/
https://www.ncbi.nlm.nih.gov/pubmed/34350211
http://dx.doi.org/10.3389/fmolb.2021.698334
work_keys_str_mv AT wuyunzhu bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT zhangruoxin bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT zhulei bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT wangweiming bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT wangshengwen bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT xiehaoran bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT chenggary bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT wangfulee bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT hexingxiang bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound
AT zhanghai bgmnetboundaryguidedmultiscalenetworkforbreastlesionsegmentationinultrasound