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BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound
Automatic and accurate segmentation of breast lesion regions from ultrasonography is an essential step for ultrasound-guided diagnosis and treatment. However, developing a desirable segmentation method is very difficult due to strong imaging artifacts e.g., speckle noise, low contrast and intensity...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326799/ https://www.ncbi.nlm.nih.gov/pubmed/34350211 http://dx.doi.org/10.3389/fmolb.2021.698334 |
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author | Wu, Yunzhu Zhang, Ruoxin Zhu, Lei Wang, Weiming Wang, Shengwen Xie, Haoran Cheng, Gary Wang, Fu Lee He, Xingxiang Zhang, Hai |
author_facet | Wu, Yunzhu Zhang, Ruoxin Zhu, Lei Wang, Weiming Wang, Shengwen Xie, Haoran Cheng, Gary Wang, Fu Lee He, Xingxiang Zhang, Hai |
author_sort | Wu, Yunzhu |
collection | PubMed |
description | Automatic and accurate segmentation of breast lesion regions from ultrasonography is an essential step for ultrasound-guided diagnosis and treatment. However, developing a desirable segmentation method is very difficult due to strong imaging artifacts e.g., speckle noise, low contrast and intensity inhomogeneity, in breast ultrasound images. To solve this problem, this paper proposes a novel boundary-guided multiscale network (BGM-Net) to boost the performance of breast lesion segmentation from ultrasound images based on the feature pyramid network (FPN). First, we develop a boundary-guided feature enhancement (BGFE) module to enhance the feature map for each FPN layer by learning a boundary map of breast lesion regions. The BGFE module improves the boundary detection capability of the FPN framework so that weak boundaries in ambiguous regions can be correctly identified. Second, we design a multiscale scheme to leverage the information from different image scales in order to tackle ultrasound artifacts. Specifically, we downsample each testing image into a coarse counterpart, and both the testing image and its coarse counterpart are input into BGM-Net to predict a fine and a coarse segmentation maps, respectively. The segmentation result is then produced by fusing the fine and the coarse segmentation maps so that breast lesion regions are accurately segmented from ultrasound images and false detections are effectively removed attributing to boundary feature enhancement and multiscale image information. We validate the performance of the proposed approach on two challenging breast ultrasound datasets, and experimental results demonstrate that our approach outperforms state-of-the-art methods. |
format | Online Article Text |
id | pubmed-8326799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83267992021-08-03 BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound Wu, Yunzhu Zhang, Ruoxin Zhu, Lei Wang, Weiming Wang, Shengwen Xie, Haoran Cheng, Gary Wang, Fu Lee He, Xingxiang Zhang, Hai Front Mol Biosci Molecular Biosciences Automatic and accurate segmentation of breast lesion regions from ultrasonography is an essential step for ultrasound-guided diagnosis and treatment. However, developing a desirable segmentation method is very difficult due to strong imaging artifacts e.g., speckle noise, low contrast and intensity inhomogeneity, in breast ultrasound images. To solve this problem, this paper proposes a novel boundary-guided multiscale network (BGM-Net) to boost the performance of breast lesion segmentation from ultrasound images based on the feature pyramid network (FPN). First, we develop a boundary-guided feature enhancement (BGFE) module to enhance the feature map for each FPN layer by learning a boundary map of breast lesion regions. The BGFE module improves the boundary detection capability of the FPN framework so that weak boundaries in ambiguous regions can be correctly identified. Second, we design a multiscale scheme to leverage the information from different image scales in order to tackle ultrasound artifacts. Specifically, we downsample each testing image into a coarse counterpart, and both the testing image and its coarse counterpart are input into BGM-Net to predict a fine and a coarse segmentation maps, respectively. The segmentation result is then produced by fusing the fine and the coarse segmentation maps so that breast lesion regions are accurately segmented from ultrasound images and false detections are effectively removed attributing to boundary feature enhancement and multiscale image information. We validate the performance of the proposed approach on two challenging breast ultrasound datasets, and experimental results demonstrate that our approach outperforms state-of-the-art methods. Frontiers Media S.A. 2021-07-19 /pmc/articles/PMC8326799/ /pubmed/34350211 http://dx.doi.org/10.3389/fmolb.2021.698334 Text en Copyright © 2021 Wu, Zhang, Zhu, Wang, Wang, Xie, Cheng, Wang, He and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Molecular Biosciences Wu, Yunzhu Zhang, Ruoxin Zhu, Lei Wang, Weiming Wang, Shengwen Xie, Haoran Cheng, Gary Wang, Fu Lee He, Xingxiang Zhang, Hai BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound |
title | BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound |
title_full | BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound |
title_fullStr | BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound |
title_full_unstemmed | BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound |
title_short | BGM-Net: Boundary-Guided Multiscale Network for Breast Lesion Segmentation in Ultrasound |
title_sort | bgm-net: boundary-guided multiscale network for breast lesion segmentation in ultrasound |
topic | Molecular Biosciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326799/ https://www.ncbi.nlm.nih.gov/pubmed/34350211 http://dx.doi.org/10.3389/fmolb.2021.698334 |
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