Case Report: Local Cytokine Release Syndrome in an Acute Lymphoblastic Leukemia Patient After Treatment With Chimeric Antigen Receptor T-Cell Therapy: A Possible Model, Literature Review and Perspective

Chimeric antigen receptor T (CAR-T) cell therapy has achieved remarkable clinical efficacy in treatment of many malignancies especially for B-cell hematologic malignancies. However, the application of CAR-T cells is hampered by potentially adverse events, of which cytokine release syndrome (CRS) is...

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Detalles Bibliográficos
Autores principales: Luan, Chengxin, Zhou, Junjie, Wang, Haixia, Ma, Xiaoyu, Long, Zhangbiao, Cheng, Xin, Chen, Xiaowen, Huang, Zhenqi, Zhang, Dagan, Xia, Ruixiang, Ge, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326907/
https://www.ncbi.nlm.nih.gov/pubmed/34349766
http://dx.doi.org/10.3389/fimmu.2021.707191

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