In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites

The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatm...

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Detalles Bibliográficos
Autores principales: Daneshmand, Ali, Young, Petrina, Campbell, Bronwyn, Kheravii, Sarbast K., Sharma, Nishchal K., Afshari, Roya, Dias, Daniel A., Flavel, Matthew, Kitchen, Barry, Wu, Shu-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326975/
https://www.ncbi.nlm.nih.gov/pubmed/34303187
http://dx.doi.org/10.1016/j.ijpddr.2021.07.001
Descripción
Sumario:The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37 °C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent.

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