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Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series

The present report describes a case series in which spacers with boluses were used at various sites in the oral cavity to enhance the therapeutic effect of radiation therapy in oral squamous cell carcinoma. In radiotherapy, the surface dose is reduced due to the build-up region of X-rays. In the pre...

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Autores principales: Yoshizawa, Kunio, Aoki, Shinichi, Marino, Kan, Matsuda, Masaki, Moroi, Akinori, Ueki, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327078/
https://www.ncbi.nlm.nih.gov/pubmed/34349987
http://dx.doi.org/10.3892/mco.2021.2349
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author Yoshizawa, Kunio
Aoki, Shinichi
Marino, Kan
Matsuda, Masaki
Moroi, Akinori
Ueki, Koichiro
author_facet Yoshizawa, Kunio
Aoki, Shinichi
Marino, Kan
Matsuda, Masaki
Moroi, Akinori
Ueki, Koichiro
author_sort Yoshizawa, Kunio
collection PubMed
description The present report describes a case series in which spacers with boluses were used at various sites in the oral cavity to enhance the therapeutic effect of radiation therapy in oral squamous cell carcinoma. In radiotherapy, the surface dose is reduced due to the build-up region of X-rays. In the present study, a bolus was used to complement the build-up region and increase the surface dose effect. A total of 7 patients with oral cancer from a primary care hospital underwent radiation therapy using spacers and added boluses to improve the surface dose effect. The spacer was made from a plastic splint and the bolus was connected to the splint with a quick self-curing resin. There were no complaints of pain or adverse events from the patients while wearing the intraoral splint. A total of 2 of the 7 patients were subsequently confirmed as having progressed disease, and the remaining 5 are currently being managed following a complete response to treatment. The spacers used at various sites of oral squamous cell carcinoma were safe and effective and did not cause any severe adverse effects.
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spelling pubmed-83270782021-08-03 Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series Yoshizawa, Kunio Aoki, Shinichi Marino, Kan Matsuda, Masaki Moroi, Akinori Ueki, Koichiro Mol Clin Oncol Articles The present report describes a case series in which spacers with boluses were used at various sites in the oral cavity to enhance the therapeutic effect of radiation therapy in oral squamous cell carcinoma. In radiotherapy, the surface dose is reduced due to the build-up region of X-rays. In the present study, a bolus was used to complement the build-up region and increase the surface dose effect. A total of 7 patients with oral cancer from a primary care hospital underwent radiation therapy using spacers and added boluses to improve the surface dose effect. The spacer was made from a plastic splint and the bolus was connected to the splint with a quick self-curing resin. There were no complaints of pain or adverse events from the patients while wearing the intraoral splint. A total of 2 of the 7 patients were subsequently confirmed as having progressed disease, and the remaining 5 are currently being managed following a complete response to treatment. The spacers used at various sites of oral squamous cell carcinoma were safe and effective and did not cause any severe adverse effects. D.A. Spandidos 2021-09 2021-07-13 /pmc/articles/PMC8327078/ /pubmed/34349987 http://dx.doi.org/10.3892/mco.2021.2349 Text en Copyright: © Yoshizawa et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Yoshizawa, Kunio
Aoki, Shinichi
Marino, Kan
Matsuda, Masaki
Moroi, Akinori
Ueki, Koichiro
Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series
title Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series
title_full Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series
title_fullStr Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series
title_full_unstemmed Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series
title_short Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series
title_sort spacers with boluses applied to various sites of oral squamous cell carcinoma: technical note and retrospective case series
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327078/
https://www.ncbi.nlm.nih.gov/pubmed/34349987
http://dx.doi.org/10.3892/mco.2021.2349
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