Cargando…
Retinyl esters form lipid droplets independently of triacylglycerol and seipin
Lipid droplets store neutral lipids, primarily triacylglycerol and steryl esters. Seipin plays a role in lipid droplet biogenesis and is thought to determine the site of lipid droplet biogenesis and the size of newly formed lipid droplets. Here we show a seipin-independent pathway of lipid droplet b...
Autores principales: | Molenaar, Martijn R., Yadav, Kamlesh K., Toulmay, Alexandre, Wassenaar, Tsjerk A., Mari, Muriel C., Caillon, Lucie, Chorlay, Aymeric, Lukmantara, Ivan E., Haaker, Maya W., Wubbolts, Richard W., Houweling, Martin, Vaandrager, Arie Bas, Prieur, Xavier, Reggiori, Fulvio, Choudhary, Vineet, Yang, Hongyuan, Schneiter, Roger, Thiam, Abdou Rachid, Prinz, William A., Helms, J. Bernd |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327380/ https://www.ncbi.nlm.nih.gov/pubmed/34323918 http://dx.doi.org/10.1083/jcb.202011071 |
Ejemplares similares
-
Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation
por: Testerink, Nicole, et al.
Publicado: (2012) -
Lipidomic profiling of rat hepatic stellate cells during activation reveals a two-stage process accompanied by increased levels of lysosomal lipids
por: Molenaar, Martijn R., et al.
Publicado: (2023) -
Seipin traps triacylglycerols to facilitate their nanoscale clustering in the endoplasmic reticulum membrane
por: Prasanna, Xavier, et al.
Publicado: (2021) -
Seipin and Nem1 establish discrete ER subdomains to initiate yeast lipid droplet biogenesis
por: Choudhary, Vineet, et al.
Publicado: (2020) -
Neutral lipids regulate amphipathic helix affinity for model lipid droplets
por: Chorlay, Aymeric, et al.
Publicado: (2020)