BTK inhibitors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): A systematic review

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INTRODUCTION: The Bruton tyrosine kinase (BTK) regulates B cell and macrophage signaling, development, survival, and activation. Inhibiting BTK has been hypothesized to ameliorate lung injury in patients with severe COVID-19, however clinical outcome data is inconclusive. OBJECTIVE: To evaluate the...

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Detalles Bibliográficos
Autores principales: Stack, Michael, Sacco, Keith, Castagnoli, Riccardo, Livinski, Alicia A., Notarangelo, Luigi D., Lionakis, Michail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327577/
https://www.ncbi.nlm.nih.gov/pubmed/34352390
http://dx.doi.org/10.1016/j.clim.2021.108816
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