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MTORC1 inhibition drives crinophagic degradation of glucagon

OBJECTIVE: Crinophagy is a secretory granule-specific autophagic process that regulates hormone content and secretion in endocrine cells. However, despite being one of the earliest described autophagic processes, its mechanism of action and regulation in mammalian cells remains unclear. METHODS AND...

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Detalles Bibliográficos
Autores principales:	Rajak, Sangam, Xie, Sherwin, Tewari, Archana, Raza, Sana, Wu, Yajun, Bay, Boon-Huat, Yen, Paul M., Sinha, Rohit A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327649/ https://www.ncbi.nlm.nih.gov/pubmed/34224916 http://dx.doi.org/10.1016/j.molmet.2021.101286

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