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Dual cytoplasmic and nuclear localization of HTLV-1-encoded HBZ protein is a unique feature of adult T-cell leukemia
Adult T-cell leukemia-lymphoma (ATL), is a highly malignant T-cell neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1), characterized by poor prognosis. Two viral proteins, Tax-1 and HTLV-1 basic-zipper factor (HBZ) play important roles in the pathogenesis of ATL. While Tax-1 can be found...
Autores principales: | Forlani, Greta, Shallak, Mariam, Tedeschi, Alessandra, Cavallari, Ilaria, Marçais, Ambroise, Hermine, Olivier, Accolla, Roberto S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327710/ https://www.ncbi.nlm.nih.gov/pubmed/33626865 http://dx.doi.org/10.3324/haematol.2020.272468 |
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