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Dual cytoplasmic and nuclear localization of HTLV-1-encoded HBZ protein is a unique feature of adult T-cell leukemia

Adult T-cell leukemia-lymphoma (ATL), is a highly malignant T-cell neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1), characterized by poor prognosis. Two viral proteins, Tax-1 and HTLV-1 basic-zipper factor (HBZ) play important roles in the pathogenesis of ATL. While Tax-1 can be found...

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Detalles Bibliográficos
Autores principales: Forlani, Greta, Shallak, Mariam, Tedeschi, Alessandra, Cavallari, Ilaria, Marçais, Ambroise, Hermine, Olivier, Accolla, Roberto S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327710/
https://www.ncbi.nlm.nih.gov/pubmed/33626865
http://dx.doi.org/10.3324/haematol.2020.272468

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