Pediatric-inspired chemotherapy incorporating pegaspargase is safe and results in high rates of minimal residual disease negativity in adults up to the age of 60 years with Philadelphia chromosome-negative acute lymphoblastic leukemia

Administration of pediatric-inspired chemotherapy to adults up to age 60 with acute lymphoblastic leukemia (ALL) is challenging in part due to toxicities of asparaginase as well as myelosuppression. We conducted a multi-center phase II clinical trial (clinicaltrials gov. Identifier: NCT01920737) inv...

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Detalles Bibliográficos
Autores principales: Geyer, Mark B., Ritchie, Ellen K., Rao, Arati V., Vemuri, Shreya, Flynn, Jessica, Hsu, Meier, Devlin, Sean M., Roshal, Mikhail, Gao, Qi, Shukla, Madhulika, Salcedo, Jose M., Maslak, Peter, Tallman, Martin S., Douer, Dan, Park, Jae H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327717/
https://www.ncbi.nlm.nih.gov/pubmed/33054114
http://dx.doi.org/10.3324/haematol.2020.251686

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