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Can Targeting Hypoxia-Mediated Acidification of the Bone Marrow Microenvironment Kill Myeloma Tumor Cells?
Multiple myeloma (MM) is an incurable cancer arising from malignant plasma cells that engraft in the bone marrow (BM). The physiology of these cancer cells within the BM microenvironment (TME) plays a critical role in MM development. These processes may be similar to what has been observed in the TM...
Autores principales: | Gastelum, Gilberto, Veena, Mysore, Lyons, Kylee, Lamb, Christopher, Jacobs, Nicole, Yamada, Alexandra, Baibussinov, Alisher, Sarafyan, Martin, Shamis, Rebeka, Kraut, Jeffry, Frost, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327776/ https://www.ncbi.nlm.nih.gov/pubmed/34350119 http://dx.doi.org/10.3389/fonc.2021.703878 |
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