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Guillain-Barré syndrome after COVID-19 vaccination

We report a case of Guillain-Barré syndrome (GBS) occurring soon after the first dose of Vaxzevria (previously known as COVID-19 vaccine AstraZeneca). Thus far, there has been no evidence of an increased risk of GBS resulting from either COVID-19 infection nor from COVID-19 vaccines; however, indivi...

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Detalles Bibliográficos
Autores principales: McKean, Norma, Chircop, Charmaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327820/
https://www.ncbi.nlm.nih.gov/pubmed/34330729
http://dx.doi.org/10.1136/bcr-2021-244125
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author McKean, Norma
Chircop, Charmaine
author_facet McKean, Norma
Chircop, Charmaine
author_sort McKean, Norma
collection PubMed
description We report a case of Guillain-Barré syndrome (GBS) occurring soon after the first dose of Vaxzevria (previously known as COVID-19 vaccine AstraZeneca). Thus far, there has been no evidence of an increased risk of GBS resulting from either COVID-19 infection nor from COVID-19 vaccines; however, individual cases and population cohorts should be scrutinised, in order to ensure the constant evaluation of such risks. It is as yet not possible to draw conclusions about any significant association between COVID-19 vaccination and GBS. A temporal correlation does not imply, and should not be deemed to signify, causality. However, it is important to remain vigilant, so that any potential increased risk is properly evaluated. The specific presentation of bifacial weakness as the initial symptom may be a characteristic feature of GBS in the context of recent COVID-19 vaccination.
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spelling pubmed-83278202021-08-19 Guillain-Barré syndrome after COVID-19 vaccination McKean, Norma Chircop, Charmaine BMJ Case Rep Case Report We report a case of Guillain-Barré syndrome (GBS) occurring soon after the first dose of Vaxzevria (previously known as COVID-19 vaccine AstraZeneca). Thus far, there has been no evidence of an increased risk of GBS resulting from either COVID-19 infection nor from COVID-19 vaccines; however, individual cases and population cohorts should be scrutinised, in order to ensure the constant evaluation of such risks. It is as yet not possible to draw conclusions about any significant association between COVID-19 vaccination and GBS. A temporal correlation does not imply, and should not be deemed to signify, causality. However, it is important to remain vigilant, so that any potential increased risk is properly evaluated. The specific presentation of bifacial weakness as the initial symptom may be a characteristic feature of GBS in the context of recent COVID-19 vaccination. BMJ Publishing Group 2021-07-30 /pmc/articles/PMC8327820/ /pubmed/34330729 http://dx.doi.org/10.1136/bcr-2021-244125 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.
spellingShingle Case Report
McKean, Norma
Chircop, Charmaine
Guillain-Barré syndrome after COVID-19 vaccination
title Guillain-Barré syndrome after COVID-19 vaccination
title_full Guillain-Barré syndrome after COVID-19 vaccination
title_fullStr Guillain-Barré syndrome after COVID-19 vaccination
title_full_unstemmed Guillain-Barré syndrome after COVID-19 vaccination
title_short Guillain-Barré syndrome after COVID-19 vaccination
title_sort guillain-barré syndrome after covid-19 vaccination
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327820/
https://www.ncbi.nlm.nih.gov/pubmed/34330729
http://dx.doi.org/10.1136/bcr-2021-244125
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