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Henoch-Schönlein Purpura With Scrotal Involvement: A Case Report and Literature Review
Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood and affects the small blood vessels, leading to arthritis, abdominal pain, and renal involvement. However, scrotal involvement is a rare complication of HSP and scrotal pain. Swelling is the most frequent clinical presentation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327932/ https://www.ncbi.nlm.nih.gov/pubmed/33885039 http://dx.doi.org/10.1097/MPH.0000000000002161 |
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author | Ma, Yue Zhang, Shanyun Chen, Jiye Kong, Han Diao, Juanjuan |
author_facet | Ma, Yue Zhang, Shanyun Chen, Jiye Kong, Han Diao, Juanjuan |
author_sort | Ma, Yue |
collection | PubMed |
description | Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood and affects the small blood vessels, leading to arthritis, abdominal pain, and renal involvement. However, scrotal involvement is a rare complication of HSP and scrotal pain. Swelling is the most frequent clinical presentation and can be easily confused with testicular torsion. If not treated in time, the scrotal inflammation will result in irreversible testicular necrosis. We report a 6-year-old male with HSP and scrotal involvement, characterized by swelling and pain on the left side of the scrotum, rashes on both lower extremities, and epididymitis. He was treated with conservative care, corticosteroids, and antibiotic therapy. We were able to avoid surgical intervention. On the 10 days of treatment, he recovered sufficiently well and was discharged. We have reviewed the literature related to HSP with scrotal involvement, identified 21 cases, and revealed that steroid therapy and/or antibiotics are the first-line of therapy in children with scrotal involvement. Vasculitis in the scrotum may predispose to testicular torsion, which is a complication that should not be overlooked. Clinicians should be aware of the atypical types of HSP. Timely diagnosis and appropriate treatment are essential for achieving the best results. |
format | Online Article Text |
id | pubmed-8327932 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-83279322021-08-02 Henoch-Schönlein Purpura With Scrotal Involvement: A Case Report and Literature Review Ma, Yue Zhang, Shanyun Chen, Jiye Kong, Han Diao, Juanjuan J Pediatr Hematol Oncol Review Articles Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood and affects the small blood vessels, leading to arthritis, abdominal pain, and renal involvement. However, scrotal involvement is a rare complication of HSP and scrotal pain. Swelling is the most frequent clinical presentation and can be easily confused with testicular torsion. If not treated in time, the scrotal inflammation will result in irreversible testicular necrosis. We report a 6-year-old male with HSP and scrotal involvement, characterized by swelling and pain on the left side of the scrotum, rashes on both lower extremities, and epididymitis. He was treated with conservative care, corticosteroids, and antibiotic therapy. We were able to avoid surgical intervention. On the 10 days of treatment, he recovered sufficiently well and was discharged. We have reviewed the literature related to HSP with scrotal involvement, identified 21 cases, and revealed that steroid therapy and/or antibiotics are the first-line of therapy in children with scrotal involvement. Vasculitis in the scrotum may predispose to testicular torsion, which is a complication that should not be overlooked. Clinicians should be aware of the atypical types of HSP. Timely diagnosis and appropriate treatment are essential for achieving the best results. Lippincott Williams & Wilkins 2021-08 2021-04-21 /pmc/articles/PMC8327932/ /pubmed/33885039 http://dx.doi.org/10.1097/MPH.0000000000002161 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (https://creativecommons.org/licenses/by/4.0/) (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Review Articles Ma, Yue Zhang, Shanyun Chen, Jiye Kong, Han Diao, Juanjuan Henoch-Schönlein Purpura With Scrotal Involvement: A Case Report and Literature Review |
title | Henoch-Schönlein Purpura With Scrotal Involvement: A Case Report and Literature Review |
title_full | Henoch-Schönlein Purpura With Scrotal Involvement: A Case Report and Literature Review |
title_fullStr | Henoch-Schönlein Purpura With Scrotal Involvement: A Case Report and Literature Review |
title_full_unstemmed | Henoch-Schönlein Purpura With Scrotal Involvement: A Case Report and Literature Review |
title_short | Henoch-Schönlein Purpura With Scrotal Involvement: A Case Report and Literature Review |
title_sort | henoch-schönlein purpura with scrotal involvement: a case report and literature review |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327932/ https://www.ncbi.nlm.nih.gov/pubmed/33885039 http://dx.doi.org/10.1097/MPH.0000000000002161 |
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