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An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer’s Disease

Alzheimer’s disease (AD) is the most frequent type of dementia. Acteoside (ACT) is a compound isolated from Cistanche tubulosa, which possesses excellent neuroprotective properties. However, the underlying mechanism of ACT in regulating microglia polarization remains ill-defined. Therefore, a comput...

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Detalles Bibliográficos
Autores principales: Li, Ying-Qi, Chen, Yi, Jiang, Si-Qi, Shi, Yuan-Yuan, Jiang, Xiao-Li, Wu, Shan-Shan, Zhou, Ping, Wang, Hui-Ying, Li, Ping, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327963/
https://www.ncbi.nlm.nih.gov/pubmed/34350171
http://dx.doi.org/10.3389/fcell.2021.652310