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Imaging in non-cystic fibrosis bronchiectasis and current limitations

Non-cystic fibrosis bronchiectasis represents a heterogenous spectrum of disorders characterised by an abnormal and permanent dilatation of the bronchial tree associated with respiratory symptoms. To date, diagnosis relies on computed tomography (CT) evidence of dilated airways. Nevertheless, defini...

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Autores principales: Ledda, Roberta Eufrasia, Balbi, Maurizio, Milone, Francesca, Ciuni, Andrea, Silva, Mario, Sverzellati, Nicola, Milanese, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328081/
https://www.ncbi.nlm.nih.gov/pubmed/34381953
http://dx.doi.org/10.1259/bjro.20210026
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author Ledda, Roberta Eufrasia
Balbi, Maurizio
Milone, Francesca
Ciuni, Andrea
Silva, Mario
Sverzellati, Nicola
Milanese, Gianluca
author_facet Ledda, Roberta Eufrasia
Balbi, Maurizio
Milone, Francesca
Ciuni, Andrea
Silva, Mario
Sverzellati, Nicola
Milanese, Gianluca
author_sort Ledda, Roberta Eufrasia
collection PubMed
description Non-cystic fibrosis bronchiectasis represents a heterogenous spectrum of disorders characterised by an abnormal and permanent dilatation of the bronchial tree associated with respiratory symptoms. To date, diagnosis relies on computed tomography (CT) evidence of dilated airways. Nevertheless, definite radiological criteria and standardised CT protocols are still to be defined. Although largely used, current radiological scoring systems have shown substantial drawbacks, mostly failing to correlate morphological abnormalities with clinical and prognostic data. In limited cases, bronchiectasis morphology and distribution, along with associated CT features, enable radiologists to confidently suggest an underlying cause. Quantitative imaging analyses have shown a potential to overcome the limitations of the current radiological criteria, but their application is still limited to a research setting. In the present review, we discuss the role of imaging and its current limitations in non-cystic fibrosis bronchiectasis. The potential of automatic quantitative approaches and artificial intelligence in such a context will be also mentioned.
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spelling pubmed-83280812021-08-10 Imaging in non-cystic fibrosis bronchiectasis and current limitations Ledda, Roberta Eufrasia Balbi, Maurizio Milone, Francesca Ciuni, Andrea Silva, Mario Sverzellati, Nicola Milanese, Gianluca BJR Open Review Article Non-cystic fibrosis bronchiectasis represents a heterogenous spectrum of disorders characterised by an abnormal and permanent dilatation of the bronchial tree associated with respiratory symptoms. To date, diagnosis relies on computed tomography (CT) evidence of dilated airways. Nevertheless, definite radiological criteria and standardised CT protocols are still to be defined. Although largely used, current radiological scoring systems have shown substantial drawbacks, mostly failing to correlate morphological abnormalities with clinical and prognostic data. In limited cases, bronchiectasis morphology and distribution, along with associated CT features, enable radiologists to confidently suggest an underlying cause. Quantitative imaging analyses have shown a potential to overcome the limitations of the current radiological criteria, but their application is still limited to a research setting. In the present review, we discuss the role of imaging and its current limitations in non-cystic fibrosis bronchiectasis. The potential of automatic quantitative approaches and artificial intelligence in such a context will be also mentioned. The British Institute of Radiology. 2021-07-29 /pmc/articles/PMC8328081/ /pubmed/34381953 http://dx.doi.org/10.1259/bjro.20210026 Text en © 2021 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Review Article
Ledda, Roberta Eufrasia
Balbi, Maurizio
Milone, Francesca
Ciuni, Andrea
Silva, Mario
Sverzellati, Nicola
Milanese, Gianluca
Imaging in non-cystic fibrosis bronchiectasis and current limitations
title Imaging in non-cystic fibrosis bronchiectasis and current limitations
title_full Imaging in non-cystic fibrosis bronchiectasis and current limitations
title_fullStr Imaging in non-cystic fibrosis bronchiectasis and current limitations
title_full_unstemmed Imaging in non-cystic fibrosis bronchiectasis and current limitations
title_short Imaging in non-cystic fibrosis bronchiectasis and current limitations
title_sort imaging in non-cystic fibrosis bronchiectasis and current limitations
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328081/
https://www.ncbi.nlm.nih.gov/pubmed/34381953
http://dx.doi.org/10.1259/bjro.20210026
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