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Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy
We report on a case of a 50-year-old female patient with primary hyperaldosteronism, in whom adrenal venous sampling was required to differentiate between unilateral and bilateral disease. Because of a history of severe allergy to iodinated contrast media, premedication with glucocorticoids was indi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328093/ https://www.ncbi.nlm.nih.gov/pubmed/34350369 http://dx.doi.org/10.1210/jendso/bvab122 |
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author | Prins, Margaretha L M Ballieux, Bartholomeus E P B Meijer, Onno C Pereira, Alberto M Nijhoff, Michiel F |
author_facet | Prins, Margaretha L M Ballieux, Bartholomeus E P B Meijer, Onno C Pereira, Alberto M Nijhoff, Michiel F |
author_sort | Prins, Margaretha L M |
collection | PubMed |
description | We report on a case of a 50-year-old female patient with primary hyperaldosteronism, in whom adrenal venous sampling was required to differentiate between unilateral and bilateral disease. Because of a history of severe allergy to iodinated contrast media, premedication with glucocorticoids was indicated. Exogenous glucocorticoids, however, can affect measurements of serum cortisol. To avoid this potential confounding effects on the cortisol assay, we decided to use dexamethasone instead of prednisolone or hydrocortisone. A high-dose adrenocorticotropin (ACTH) stimulation test with the simultaneous use of dexamethasone revealed an adequate adrenal cortisol response. ACTH-stimulated adrenal venous sampling showed reliable results, which provided a solid basis for further clinical decision-making. |
format | Online Article Text |
id | pubmed-8328093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-83280932021-08-03 Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy Prins, Margaretha L M Ballieux, Bartholomeus E P B Meijer, Onno C Pereira, Alberto M Nijhoff, Michiel F J Endocr Soc Case Report We report on a case of a 50-year-old female patient with primary hyperaldosteronism, in whom adrenal venous sampling was required to differentiate between unilateral and bilateral disease. Because of a history of severe allergy to iodinated contrast media, premedication with glucocorticoids was indicated. Exogenous glucocorticoids, however, can affect measurements of serum cortisol. To avoid this potential confounding effects on the cortisol assay, we decided to use dexamethasone instead of prednisolone or hydrocortisone. A high-dose adrenocorticotropin (ACTH) stimulation test with the simultaneous use of dexamethasone revealed an adequate adrenal cortisol response. ACTH-stimulated adrenal venous sampling showed reliable results, which provided a solid basis for further clinical decision-making. Oxford University Press 2021-07-12 /pmc/articles/PMC8328093/ /pubmed/34350369 http://dx.doi.org/10.1210/jendso/bvab122 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Prins, Margaretha L M Ballieux, Bartholomeus E P B Meijer, Onno C Pereira, Alberto M Nijhoff, Michiel F Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy |
title | Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy |
title_full | Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy |
title_fullStr | Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy |
title_full_unstemmed | Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy |
title_short | Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy |
title_sort | adrenal vein sampling in a patient with primary hyperaldosteronism and severe contrast allergy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328093/ https://www.ncbi.nlm.nih.gov/pubmed/34350369 http://dx.doi.org/10.1210/jendso/bvab122 |
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