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TREM-1(+) Macrophages Define a Pathogenic Cell Subset in the Intestine of Crohn’s Disease Patients
BACKGROUND AND AIMS: Uncontrolled activation of intestinal mononuclear phagocytes [MNPs] drives chronic inflammation in inflammatory bowel disease [IBD]. Triggering receptor expressed on myeloid cells 1 [TREM-1] has been implicated in the pathogenesis of IBD. However, the role of TREM-1(+) cell subs...
Autores principales: | Caër, Charles, Gorreja, Frida, Forsskåhl, Sophia K, Brynjolfsson, Siggeir F, Szeponik, Louis, Magnusson, Maria K, Börjesson, Lars G, Block, Mattias, Bexe-Lindskog, Elinor, Wick, Mary Jo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328300/ https://www.ncbi.nlm.nih.gov/pubmed/33537747 http://dx.doi.org/10.1093/ecco-jcc/jjab022 |
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