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Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection

The development of a safe and effective vaccine is a key requirement to overcoming the COVID-19 pandemic. Recombinant proteins represent the most reliable and safe vaccine approach but generally require a suitable adjuvant for robust and durable immunity. We used the SARS-CoV-2 genomic sequence and...

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Detalles Bibliográficos
Autores principales: Li, Lei, Honda-Okubo, Yoshikazu, Huang, Ying, Jang, Hyesun, Carlock, Michael A., Baldwin, Jeremy, Piplani, Sakshi, Bebin-Blackwell, Anne G., Forgacs, David, Sakamoto, Kaori, Stella, Alberto, Turville, Stuart, Chataway, Tim, Colella, Alex, Triccas, Jamie, Ross, Ted M., Petrovsky, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328570/
https://www.ncbi.nlm.nih.gov/pubmed/34420786
http://dx.doi.org/10.1016/j.vaccine.2021.07.087