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Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection
The development of a safe and effective vaccine is a key requirement to overcoming the COVID-19 pandemic. Recombinant proteins represent the most reliable and safe vaccine approach but generally require a suitable adjuvant for robust and durable immunity. We used the SARS-CoV-2 genomic sequence and...
Autores principales: | Li, Lei, Honda-Okubo, Yoshikazu, Huang, Ying, Jang, Hyesun, Carlock, Michael A., Baldwin, Jeremy, Piplani, Sakshi, Bebin-Blackwell, Anne G., Forgacs, David, Sakamoto, Kaori, Stella, Alberto, Turville, Stuart, Chataway, Tim, Colella, Alex, Triccas, Jamie, Ross, Ted M., Petrovsky, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328570/ https://www.ncbi.nlm.nih.gov/pubmed/34420786 http://dx.doi.org/10.1016/j.vaccine.2021.07.087 |
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