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Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura

COVID-19 most related glomerular disease to date seems to be collapsing glomerulopathy, mostly in young Afroamerican patients with APOL1 gene risk alleles. However, in our population, predominant in elderly Caucasian patients, most biopsied pathology since the beginning of the pandemic has been IgA...

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Autores principales: Oñate, Irene, Ortiz, Milagros, Suso, Andrea, Mon, Carmen, Galindo, Karen, Lentisco, Carolina, Camacho, Rosa, Sánchez, María, Oliet, Aniana, Ortega, Olimpia, Herrero, Juan C., Cortés, José A., Pascual, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328573/
https://www.ncbi.nlm.nih.gov/pubmed/34366528
http://dx.doi.org/10.1016/j.nefro.2021.07.009
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author Oñate, Irene
Ortiz, Milagros
Suso, Andrea
Mon, Carmen
Galindo, Karen
Lentisco, Carolina
Camacho, Rosa
Sánchez, María
Oliet, Aniana
Ortega, Olimpia
Herrero, Juan C.
Cortés, José A.
Pascual, Alejandro
author_facet Oñate, Irene
Ortiz, Milagros
Suso, Andrea
Mon, Carmen
Galindo, Karen
Lentisco, Carolina
Camacho, Rosa
Sánchez, María
Oliet, Aniana
Ortega, Olimpia
Herrero, Juan C.
Cortés, José A.
Pascual, Alejandro
author_sort Oñate, Irene
collection PubMed
description COVID-19 most related glomerular disease to date seems to be collapsing glomerulopathy, mostly in young Afroamerican patients with APOL1 gene risk alleles. However, in our population, predominant in elderly Caucasian patients, most biopsied pathology since the beginning of the pandemic has been IgA nephritis or Schönlein-Henoch purpura. Since the description of the first case of this entity after SARS-CoV-2 infection by our research group, three more cases have arisen, which are described in the following article. In contrast to the rest of IgA vasculitis cases reported, our patients presented more renal function deterioration and all of them required immunosupresive therapy. Moreover, some showed incomplete recovery of renal function. This case series strengthens the hypothesis that SARS-CoV-2 infection may be another trigger of this pathology.
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spelling pubmed-83285732021-08-03 Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura Oñate, Irene Ortiz, Milagros Suso, Andrea Mon, Carmen Galindo, Karen Lentisco, Carolina Camacho, Rosa Sánchez, María Oliet, Aniana Ortega, Olimpia Herrero, Juan C. Cortés, José A. Pascual, Alejandro Nefrologia Caso Clínico COVID-19 most related glomerular disease to date seems to be collapsing glomerulopathy, mostly in young Afroamerican patients with APOL1 gene risk alleles. However, in our population, predominant in elderly Caucasian patients, most biopsied pathology since the beginning of the pandemic has been IgA nephritis or Schönlein-Henoch purpura. Since the description of the first case of this entity after SARS-CoV-2 infection by our research group, three more cases have arisen, which are described in the following article. In contrast to the rest of IgA vasculitis cases reported, our patients presented more renal function deterioration and all of them required immunosupresive therapy. Moreover, some showed incomplete recovery of renal function. This case series strengthens the hypothesis that SARS-CoV-2 infection may be another trigger of this pathology. Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. 2022 2021-08-03 /pmc/articles/PMC8328573/ /pubmed/34366528 http://dx.doi.org/10.1016/j.nefro.2021.07.009 Text en © 2021 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Caso Clínico
Oñate, Irene
Ortiz, Milagros
Suso, Andrea
Mon, Carmen
Galindo, Karen
Lentisco, Carolina
Camacho, Rosa
Sánchez, María
Oliet, Aniana
Ortega, Olimpia
Herrero, Juan C.
Cortés, José A.
Pascual, Alejandro
Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura
title Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura
title_full Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura
title_fullStr Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura
title_full_unstemmed Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura
title_short Vasculitis IgA con nefritis (púrpura de Schönlein-Henoch) tras COVID-19: una serie de casos y revisión de la literatura
title_sort vasculitis iga con nefritis (púrpura de schönlein-henoch) tras covid-19: una serie de casos y revisión de la literatura
topic Caso Clínico
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328573/
https://www.ncbi.nlm.nih.gov/pubmed/34366528
http://dx.doi.org/10.1016/j.nefro.2021.07.009
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