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Mammoth Giant Cell Tumor of the First Metacarpal: A Case Report and Management Trends
Giant cell tumor (GCT) is classically described as a locally aggressive, epiphyseo-metaphyseal osteolytic tumor occurring in young adults. They are mostly seen in long bones while some are also found in the iliac bone and spine and a very small proportion occurs in hand bones. Due to the rarity of G...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328844/ https://www.ncbi.nlm.nih.gov/pubmed/34354887 http://dx.doi.org/10.7759/cureus.16150 |
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author | Agrawal, Alok C Verma, Shilp Kar, Bikram Sakale, Harshal Choudhary, Ranjeet |
author_facet | Agrawal, Alok C Verma, Shilp Kar, Bikram Sakale, Harshal Choudhary, Ranjeet |
author_sort | Agrawal, Alok C |
collection | PubMed |
description | Giant cell tumor (GCT) is classically described as a locally aggressive, epiphyseo-metaphyseal osteolytic tumor occurring in young adults. They are mostly seen in long bones while some are also found in the iliac bone and spine and a very small proportion occurs in hand bones. Due to the rarity of GCT in metacarpal, there is a paucity of treatment options available. In an extensive literature search on PubMed, Embase, Medline, and Ovid from 2004 till date, very few cases were reported. The various treatment options available are intralesional curettage with or without adjuvant therapy, wide resection, free osteoarticular metatarsal transfer, and, occasionally, ray amputation may also be done. After simple curettage, a reasonably high recurrence rate also imposes comprehensive en-bloc excision, but still, there are many case reports of recurrence. Experience with a case of GCT of the whole first metacarpal extending from the carpometacarpal to the metacarpophalangeal joint is not thoroughly described in the literature. We hereby report a mammoth GCT of the first metacarpal treated by excision and reconstruction by free fibular graft and adjacent joint fusion with an excellent functional outcome at one-year follow-up. |
format | Online Article Text |
id | pubmed-8328844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-83288442021-08-04 Mammoth Giant Cell Tumor of the First Metacarpal: A Case Report and Management Trends Agrawal, Alok C Verma, Shilp Kar, Bikram Sakale, Harshal Choudhary, Ranjeet Cureus Oncology Giant cell tumor (GCT) is classically described as a locally aggressive, epiphyseo-metaphyseal osteolytic tumor occurring in young adults. They are mostly seen in long bones while some are also found in the iliac bone and spine and a very small proportion occurs in hand bones. Due to the rarity of GCT in metacarpal, there is a paucity of treatment options available. In an extensive literature search on PubMed, Embase, Medline, and Ovid from 2004 till date, very few cases were reported. The various treatment options available are intralesional curettage with or without adjuvant therapy, wide resection, free osteoarticular metatarsal transfer, and, occasionally, ray amputation may also be done. After simple curettage, a reasonably high recurrence rate also imposes comprehensive en-bloc excision, but still, there are many case reports of recurrence. Experience with a case of GCT of the whole first metacarpal extending from the carpometacarpal to the metacarpophalangeal joint is not thoroughly described in the literature. We hereby report a mammoth GCT of the first metacarpal treated by excision and reconstruction by free fibular graft and adjacent joint fusion with an excellent functional outcome at one-year follow-up. Cureus 2021-07-03 /pmc/articles/PMC8328844/ /pubmed/34354887 http://dx.doi.org/10.7759/cureus.16150 Text en Copyright © 2021, Agrawal et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Oncology Agrawal, Alok C Verma, Shilp Kar, Bikram Sakale, Harshal Choudhary, Ranjeet Mammoth Giant Cell Tumor of the First Metacarpal: A Case Report and Management Trends |
title | Mammoth Giant Cell Tumor of the First Metacarpal: A Case Report and Management Trends |
title_full | Mammoth Giant Cell Tumor of the First Metacarpal: A Case Report and Management Trends |
title_fullStr | Mammoth Giant Cell Tumor of the First Metacarpal: A Case Report and Management Trends |
title_full_unstemmed | Mammoth Giant Cell Tumor of the First Metacarpal: A Case Report and Management Trends |
title_short | Mammoth Giant Cell Tumor of the First Metacarpal: A Case Report and Management Trends |
title_sort | mammoth giant cell tumor of the first metacarpal: a case report and management trends |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328844/ https://www.ncbi.nlm.nih.gov/pubmed/34354887 http://dx.doi.org/10.7759/cureus.16150 |
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