Cargando…
Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection
The generation of a human pancreatic beta cell line which reproduces the responses seen in primary beta cells, but is amenable to propagation in culture, has long been an important goal in diabetes research. This is particularly true for studies focussing on the role of enteroviral infection as a po...
Autores principales: | Chaffey, Jessica R., Young, Jay, Leslie, Kaiyven A., Partridge, Katie, Akhbari, Pouria, Dhayal, Shalinee, Hill, Jessica L., Wedgwood, Kyle C. A., Burnett, Edward, Russell, Mark A., Richardson, Sarah J., Morgan, Noel G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329048/ https://www.ncbi.nlm.nih.gov/pubmed/34341375 http://dx.doi.org/10.1038/s41598-021-94878-y |
Ejemplares similares
-
Temporal regulation of interferon signalling in human EndoC-βH1 cells
por: Dhayal, Shalinee, et al.
Publicado: (2022) -
Type 1 Diabetes: Interferons and the Aftermath of Pancreatic Beta-Cell Enteroviral Infection
por: Akhbari, Pouria, et al.
Publicado: (2020) -
The transcription factor STAT6 plays a critical role in promoting beta cell viability and is depleted in islets of individuals with type 1 diabetes
por: Leslie, Kaiyven A., et al.
Publicado: (2018) -
Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes
por: Dunne, Jessica L., et al.
Publicado: (2019) -
Enteroviral infections in the pathogenesis of type 1 diabetes: new insights for therapeutic intervention
por: Richardson, Sarah J, et al.
Publicado: (2018)