A deep convolutional neural network for segmentation of whole-slide pathology images identifies novel tumour cell-perivascular niche interactions that are associated with poor survival in glioblastoma

BACKGROUND: Glioblastoma is the most aggressive type of brain cancer with high-levels of intra- and inter-tumour heterogeneity that contribute to its rapid growth and invasion within the brain. However, a spatial characterisation of gene signatures and the cell types expressing these in different tu...

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Detalles Bibliográficos
Autores principales: Zadeh Shirazi, Amin, McDonnell, Mark D., Fornaciari, Eric, Bagherian, Narjes Sadat, Scheer, Kaitlin G., Samuel, Michael S., Yaghoobi, Mahdi, Ormsby, Rebecca J., Poonnoose, Santosh, Tumes, Damon J., Gomez, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329064/
https://www.ncbi.nlm.nih.gov/pubmed/33927352
http://dx.doi.org/10.1038/s41416-021-01394-x

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